
To me, the most interesting character in the  history of angioplasty was Andreas Gruentzig, a German Cardiologist, who  first learnt of the angioplasty technique at a lecture by the American  doctor Charles Dotter in the late 1960s. The method he observed did not  use a balloon, but pushed a catheter through an occluded artery, a bit  like a pipe cleaner.
Gruentzig hypothesised that a balloon catheter would be an improvement,  however, he encountered resistance to his work to develop a balloon  catheter in Germany so moved to Zurich in 1969.
Gruentzig  presented the theory of his balloon catheter to the 1975 AHA meeting  (American Heart Association). This was unfortunately met by widespread  scepticism.  However, Dr. Richard Myler did see potential in the  technique and  invited Gruentzig to San Francisco where they performed a  direct method on  an anaesthetised patient during by-pass surgery. This  first attempt was a success.
On his return to Zurich the work  continued and on September 16th, 1977, in the University Hospital, the  first  transluminal coronary angioplasty (PTCA) procedure on an awake  patient with a balloon catheter was performed. This was with a catheter  he made in his kitchen!
He expanded a 3mm section of the left  anterior descending (LAD) artery. The immediate results were very good,  with the patient remaining angina free. The patient was followed up on  the 10 year anniversary of the procedure and the artery remained almost  perfectly expanded. An excellent result, even by today's standards!
Gruentzig  returned to the 1977 meeting of the AHA with the results of his first  four cases. This time he was rewarded with a standing ovation. His  amazing breakthrough and contribution to the future of cardiology  acknowledged by his peers.
Gruentzig felt it was extremely  important that he pass the techniques involved in this new procedure on  himself. He was concerned that clinicians would not understand the risks  and pitfalls without his guidance. He also continued to make catheters  himself and kept this under tight control and distributed his creations  with great care.
In late 1980 Gruentzig moved to Atlanta, having  felt stifled by the bureaucracy in Europe.
Unfortunately, in  October 1985, Andreas Gruentzig and his wife were killed in a plane  crash in stormy weather, he was piloting the plane at the time. He was  only 46 years old.
Amazingly, the catheters used today are still  of a similar design to those designed on a kitchen table in the 1970's.  His death was a great loss to the world of medicine.